Novel derivatives of oleic acid effectively inhibiting ferroptosis that could be used for treatment of Friedreich Ataxia, neurodegenerative diseases, and neuropsychiatric diseases.
shRNA library of 3 million sequences for identification of small-RNA therapeutic candidates, new targets and pathways, as well as conventional chemical-compound drugs in cell-culture disease models.
A novel treatment for rare disease Friedreich ataxia using p38 or MK2 kinase inhibitors
New compounds identified through high throughput screening which improve mitochondrial function of Friedreich ataxia cells.