Search Results - e.+james+petersson

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Peptide Inhibitor to Treat Cancers and COVID-19 While Decreasing Off-Target Side Effects

Thioamide-stabilized peptide specifically inhibiting cathepsin L to block SARS-CoV-2 entry and cancer cell migration

Published: 10/30/2023
Inventor(s):
E. James Petersson, Hoang Anh T. Phan
Keywords(s):
Immunology, Immunoncology, Oncology
Category(s):
Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Vaccines

Non-perturbative, site-specific labeling of α-synuclein for studying amyloid disease and screening therapeutics

Fluorescently labeled α-synuclein to examine destabilization of synuclein fibrils by small molecules and therapeutics for neurodegenerative diseases 

Published: 10/30/2023
Inventor(s):
E. James Petersson
Keywords(s):
 
Category(s):
Technology Classifications > Physical Sciences > Chemical Processes and Synthesis, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Imaging, Technology Classifications > Life Sciences > Research Tools & Reagents, Technology Classifications > Life Sciences > Therapeutics

Thioamide-modified peptides for stabilized therapeutics and drug development

Natural bioactive peptides and hormones with thioamide substitutions at cleavage sites for improved pharmacokinetics

Published: 10/30/2023
Inventor(s):
E. James Petersson
Keywords(s):
 
Category(s):
Technology Classifications > Physical Sciences > Chemical Processes and Synthesis, Technology Classifications > Physical Sciences > Materials, Technology Classifications > Life Sciences > Therapeutics

One step N-terminal tagging of endogenous proteins for therapeutic delivery, diagnostics, and in vivo imaging

N-Terminal protein modification using adenosine substrates and aminoacyl transferase

Published: 10/30/2023
Inventor(s):
E. James Petersson, Alan Saghatelian
Keywords(s):
 
Category(s):
Technology Classifications > Physical Sciences > Chemical Processes and Synthesis, Technology Classifications > Life Sciences > Research Tools & Reagents, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Therapeutics