Search Results - cardiovascular

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VASH1 Depletion for Heart Failure Therapy

Non-replicating viral delivery of shVASH1 to treat heart failure.

Published: 10/30/2023
Inventor(s):
Benjamin Prosser, Kenneth Margulies, Alexey Bogush
Keywords(s):
Cardiovascular
Category(s):
Technology Classifications > Life Sciences > Therapeutics

Naturally flexible, adhesive, and conductive hydrogel electrodes for medical sensing

A hydrogel that combines conductive additives with the strength of dynamic bonds to create a naturally flexible and adhesive electrode.  

Published: 10/30/2023
Inventor(s):
Flavia Vitale, Shu Yang, Mehrnaz Mojtabavi, Brendan Murphy, Mingtao Chen, Baohong Chen, Yuchong Gao
Keywords(s):
Bioengineering, Cardiovascular, Hydrogels, Neurology, Soft Materials
Category(s):
Technology Classifications > Physical Sciences > Materials, Technology Classifications > Life Sciences > Medical Devices

Efficient and easy-to-use decision support tool for coronary artery disease tests

Tool that evaluates the utility of various tests for coronary artery disease, saving time by allowing non-cardiologists to order an appropriate test.

Published: 10/30/2023
Inventor(s):
Jonathan Gomberg
Keywords(s):
Cardiovascular
Category(s):
Technology Classifications > Life Sciences > Diagnostics

Histone deacetylase and DNA methyltransferase inhibitors for preventative cardiac care and ischemic injury treatment

HDAC and DNMT Inhibitors such as Trichostatin A (TSA) and 5-aza-cytidine are preventative therapies and reduce myocardial infarct volume following cardiac events

Published: 10/30/2023
Inventor(s):
Jonathan Epstein, Peter Gruber, Ibrahim Abdullah
Keywords(s):
Cardiovascular
Category(s):
Technology Classifications > Life Sciences > Therapeutics

Targeted drug delivery using red-blood cells for transport

Platform technology for targeted drug delivery using red blood cells for transport. 

Published: 10/30/2023
Inventor(s):
Laura Ferguson, Elizabeth Hood, Carlos Villa, Jacob Brenner, Vladimir Muzykantov
Keywords(s):
Cardiovascular, COVID-19, Drug Delivery, Nanotechnology, Pulmonary
Category(s):
Technology Classifications > Life Sciences > Therapeutics

New device for aortic repair and replacement

Professors from Penn Cardiothoracic Surgery have designed a single device that is able to replace the aortic valve and repair the ascending aorta in one procedure.

Published: 10/30/2023
Inventor(s):
Bartosz Rylski, Karianna Milewski, Joseph Bavaria
Keywords(s):
Cardiovascular
Category(s):
Technology Classifications > Life Sciences > Medical Devices

Heart disease diagnostic and prognostic

Indicators for treatment of bicuspid aortic valve and aortopathies.

Published: 10/30/2023
Inventor(s):
Giovanni Ferrari, Emanuela Branchetti
Keywords(s):
Cardiovascular
Category(s):
Technology Classifications > Life Sciences > Diagnostics

Neuregulin-1beta as a biomarker in heart failure and chemotherapy-related cardiotoxicity

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Published: 10/30/2023
Inventor(s):
Bonnie Ky, Thomas Cappola
Keywords(s):
Cardiovascular
Category(s):
Technology Classifications > Life Sciences > Research Tools & Reagents

Guidance device for optimized directional placement of chest tubes

A plastic device to guide directional placement of chest tubes. Unlike chest tube placement without guidance when using kelly clamps for stability, the chest tube guidance device places the tube in its intended intrathoracic direction correctly in the first instance, thereby avoiding repeat procedures and injury.

Published: 10/30/2023
Inventor(s):
Shariq Raza
Keywords(s):
Cardiovascular, Surgery
Category(s):
Technology Classifications > Life Sciences > Medical Devices

Microfabricated device for measuring and manipulating human cardiac tissue

Engineered cardiac microtissues embedded within 3D micropatterned matrices

Published: 10/30/2023
Inventor(s):
Christopher Chen
Keywords(s):
Cardiovascular
Category(s):
Technology Classifications > Life Sciences > Medical Devices, Technology Classifications > Life Sciences > Research Tools & Reagents