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A method that maintains the viability and function of NK cells following cryopreservation, enabling the production, storage, and transportation of therapeutic doses of NK cells to treatment centers.
Hydroxycholesterols are used to formulate lipid nanoparticles (LNPs) for enhanced mRNA delivery into T cells.
The deep learning algorithm retrospectively improves the resolution of routine medical images (e.g., CT, MRI, etc.) without the need for increased radiation or scan time.
Co-expression of modified chimeric antigen receptor (CAR) T cells and cholesterol 25-hydroxylase (CH25H) in a single construct for treatment of solid tumor and hematological cancers.
Nanocluster agents that enable imaging through cyanine dyes and/or photosensitizers without the need for additional carrier molecules.
Ten candidate serum and synovial protein levels provide early indication of joint impairment in lysosomal storage disorders.
A platform to isolate and expand CD137-positive (CD137pos) tumor-infiltrating lymphocytes (TILs) to use in adoptive immunotherapy and translational studies.
Nanoparticles for potent encapsulation and delivery of therapeutic molecules for prenatal fetal therapy in the amniotic sac
A platform technology utilizing synthetic organelles to modulate cell cycle, cell behavior, and stemness/differentiation status which could be used for cell engineering, cell therapy etc.