An ultrasensitive diagnostic tool that isolates single extracellular vesicles (EVs) and measures their contents to single molecule resolution.
A combinatorial library of RGD peptide (arginine-glycine-aspartic acid)-based lipids designed to formulate lipid nanoparticles for targeted mRNA delivery to the liver and the spleen.
Hydroxycholesterols are used to formulate lipid nanoparticles (LNPs) for enhanced mRNA delivery into T cells.
A hydrogel-based, strong adhesive with fast and reversible thermally activated bonding for use in various environments.
Ultrastrong hydrogel adhesives that can carry greater than 50kgs of weight and yet can be rendered reversible.
A cloud-based machine learning platform accessible by clinicians for real-time image analysis supporting multiple machine learning algorithms.
Lipid nanoparticles for selective mRNA delivery to the placenta to treat pre-eclampsia, FGR, and other pregnancy-related disorders.
A novel LNP formulation that allows for the conjugation of a chemotherapeutic agent to small interfering RNA (siRNA)-loaded LNP.
Co-expression of modified chimeric antigen receptor (CAR) T cells and cholesterol 25-hydroxylase (CH25H) in a single construct for treatment of solid tumor and hematological cancers.
A library of bi-phosphonate ionizable lipids and LNP formulations to facilitate mRNA delivery to the bone microenvironment.