Small molecule therapeutics that aid in clearing abnormal protein deposits observed in neurodegenerative diseases.
Compounds are designed to detect and characterize specific RNAs in a cell or sub-cellular compartment using light activation.
A novel LNP formulation that allows for the conjugation of a chemotherapeutic agent to small interfering RNA (siRNA)-loaded LNP.
Method to micropattern the channels in a Very Large Scale Microfluidic Integrated (VLSMI) chip for high throughput multi-order emulsion production.
[%brief%]
Small molecule inhibitors of a key cancer cell signaling pathway cause hematologic cancer cell death, but have low toxicity towards healthy cells.
Brain penetrating compounds as promising therapeutics for treatment of neurodegenerative disorders.
Inhibitors and tools to block the local formation of steroid hormones in hormone-dependent malignancies of the prostate, breast and endometrium
Therapeutic development for HIV-1 infection and prevention of transmission
Antiviral compounds that competitively disrupt virus-host interactions to inhibit disease progression and transmission